Pyroluria anxiety and depression comes from a genetic abnormality with hemoglobin metabolism. There are many symptoms of pyroluria, which is why this condition is often misdiagnosed. However, the pyroluria test is a simple, inexpensive urine test which measures levels of kryptopyrrole. This urinalysis is available from our office.

Once pyroluria is determined, treatment involves supplementing vitamin B6 and zinc at high enough levels to correct the imbalance. Additionally, patients who test positive for pyroluria must avoid fish oil, copper, and red & yellow food dyes.

This simple treatment should provide results anywhere within two days to two weeks – depending on the severity of pyroluria. Because pyroluria can be a genetic condition, supplementation must continue to avoid the return of symptoms.

• Depression
• Anxiety
• Bipolar disorder
• Schizophrenia
• Mood swings
• Poor reaction to stress
• Unexplained nausea
• Weak appetite in the morning
• Hypoglycemia
• Panic attacks
• Fatigue
• Tendency for addictive behavior
• Poor dream recall
• Allergies
• Joint pain
• Antisocial tendencies that worsen with age
• Motion sickness
• Frequent infections

Histadelia or “undermethylation” indicates high levels of histamine in the bloodstream and can be discovered through testing of the whole blood histamine level, folic acid, and basophil levels. There are histamine receptors all through the body, in the skin, lungs, blood vessels, and mucous membranes, so undermethylation treatment can benefit both emotional and physical symptoms.

High histamine can be caused by metabolic imbalances that result from many factors such as low vitamin B6 that acts as a cofactor to convert histidine to histamine, gut bacteria that cause elevated histamine, histamine from foods that you eat, estrogen levels (high estrogen will elevate histamine levels and high histamine can elevate estrogen levels) etc. It seems there is a lot more to histamine levels than just proper methylation.

Treatment for undermethylation revolves around utilizing natural methods to help histamine leave the body and support metabolism. This includes supplements such as methionine, calcium, and other supportive nutrients. It often takes three to six months to resolve this chemical imbalance. If treatment is discontinued, symptoms will return.

HISTADELIA
SYMPTOMS

• Depression
• Anxiety
• Bipolar disorder
• Schizophrenia
• Mood swings
• Poor reaction to stress
• Unexplained nausea
• Weak appetite in the morning
• Hypoglycemia
• Panic attacks
• Fatigue
• Tendency for addictive behavior
• Poor dream recall
• Allergies
• Joint pain
• Antisocial tendencies that worsen with age
• Motion sickness
• Frequent infections

Histapenia or “overmethylation” indicates low blood histamine levels. This condition can cause an increase in the production of the neurotransmitter dopamine, contributing to anxiety disorders. Histapenia can be diagnosed with a blood test, which we can administer here at the clinic.

Overmethylation can be treated naturally with nutritional supplementation. Treatment revolves around folic acid, niacin, B12, and a high protein diet. Once the patient has begun treatment, they should see a gradual improvement within two to four weeks, with full correction occurring over a period of several months. This condition is associated with a biological dependence on these nutrients, so if treatment is discontinued, symptoms will return.

• Anxiety
• Nervousness
• Social isolation
• Depression
• Food & chemical sensitivities
• Panic attacks
• Paranoia
• Learning disabilities
• Academic underachievement
• Restless legs
• Dry eyes
• Heavy body hair